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QUESTION:

Hi -
It's me, and I'm back with another question for you.

This time I'm writing about my family in the Philippines.  My wife  is
Filipina and her brother and his family live near Manila along with her Dad. Anyway, I was talking to R (her brother) the other day and he mentioned that F (one of my nieces)   was feverish and "not feeling well" (which probably means she was not as active) and that he had given her some antibiotics. I asked about the antibiotics. He said he gave her Bactrim (trimethoprim/sulfamethoxazole). I asked him where he got it and he said "at the drug store." I asked him if he got a prescription from a doctor for it and he said "no" and that they could just purchase antibiotics OTC. He further stated that they "usually give that for a few days when people are sick."

I know in this country we "try" not to give antibiotics to people unless we
believe they might benefit from it, and that we are trying to cut down on
indiscriminate use of antibiotics because it promotes the evolution of
antibiotic-resistant strains of bacteria. I also know that taking  antibiotics for a couple of days and then stopping is not good because it  promotes the growth of antibiotic-resistant bacteria in the body (and I explained that to R).

My question to you is this. Considering the relative ease with which  antibiotics are obtained in the Philippines, what should I tell R about when is the appropriate time to take them? How does one tell, generally, if an illness would benefit from antibiotic treatment? Are there some basic rules of thumb for when to and when not to take them (kind of like "starve a fever, feed a cold", except for antibiotics)?

I discussed with R the possibility of never giving antibiotics to his family unless he was prescribed to do so by a physician. However, R said physicians almost always give antibiotics to anyone who isn't feeling well (great!). I know that many US physicians also do that to make it look like they're trying to help a patient (present company excepted, I'm sure), even though it's not helping at all, so I can only imagine that the trend is worse over there where the medical expertise is at a lower standard.

Any guidance would be greatly appreciated.

ANSWER:

Apologize for taking somewhat longer to answer this for you, but I was
detained by a lovely 7#14oz baby girl coming into the world yesterday.  I'm
sure you'll understand! Welcome back - again with another good question.  You have hit on a problem that illustrates our global culture and the difficulties it presents.   Even in the U.S. we are overusing antibiotics, partially due to laziness on the part of providers and largely due to insistent demand on the part of consumer/patients.   The Center for Disease Control is making an effort to stop the trend, but of course they only reach a part of the population and have very little effect on the people in other countries.

You are quite right in your assumptions and your concerns.  Bactrim, otherwise known as Septra, is a basic and very good antibiotic.  I can not say the the over-the-counter type they sell in other countries is pure or standardized for effectiveness but giving it in the way you describe is definitely NOT a good idea. The body, repeatedly exposed to the Septra,will develop within its immune system adjustments that will make it less effective when it is truly needed.  In addition, a true infection only partially treated with antibiotics often recurs - but resistent to the initial antibiotic.  People are also somewhat more likely to develop allergic reactions or intolerance to specific antibiotics, not a small
thing with Bactrim!  The allergic reaction to Bactrim can be life threatening. But I tell you what you already know.....

Antibiotics, like any powerful ally in health care, should be used with great respect for their power.  How to tell when to use them?  As a doctor, I use all my diagnostic skills and scopes to make that decision.  A large part of it is my ability to tell after all these years who is really sick and needs the big guns.  It's an observation skill.....  However, I know many mothers who are quite skilled at knowing when their family members are truly sick and they don't even ask for antibiotics until it is appropriate.  After awhile I trust these parents and when they call me and describe the problem, I believe them when they say they need antibiotic help.

In answer to your question:  No, there is not a rule of thumb that is simple for this one.  But there is a valuable guideline:  Do NOT use antibiotics unless the person is obviously toxic (persistent fever, actual pus seen somewhere) or unless their own immune system has not been able to win the fight after two weeks of trying.   Seeing pus behind the ear drum, hearing congestion within the lungs, seeing an infected skin lesion, or having a positive strep culture from the throat are all worth antibiotics. But a thoughtful provider has to make that call, usually.  Viruses can cause very high fevers, can cause white spots on the tonsils, and can make a person look sicker than a bacterial infection. Viruses are not touched by antibiotics.

Again, I give you some internet resources here that are appropriate.  Try this link to the CDC's site:

http://www.cdc.gov/drugresistance/community/

and then you can try their 'FAQ' page:

http://www.cdc.gov/drugresistance/community/


Good luck trying to convince your family in the Philippines to avoid antibiotics unless really needed!  I know from experience that re-educating ourselves about this is difficult and it is hard to watch your children feel bad if you think there might be an easy solution.  I encourage people to honor their own powerful immune system and allow it to do its job, but they don't always like to hear it.

Best Wishes,

Dr. Kerr

Last modified: 10/04/2007                                                    Hit Counter